İsmail ŞEN | Hasan GÜZELBEKTEŞ

Article | 2019 | MANAS Journal of Agriculture, Veterinary and Life Science (MJAVL)9 ( 2 )

Buzağılara IgG’nin transferi olarak adlandırılan pasif immune transfer ancak maternal kolostrum alınmasıyla gerçekleşir. Yetersiz kolostral IgG’nin alımı ya da absorbsiyonu pasif transfer yetmezliğine neden olmaktadır. Buzağılarda pasif transfer yetmezliğin belirlenmesi için çeşitli analiz metodları bulunmaktadır. Bu derlemede buzağılarda pasif transfer yetmezliğin tespitinde kullanılan yöntemler ve bu yöntemlerin avantaj ve dezavantajları anlatılmıştır.

İsmail ŞEN

Article | 2019 | International Journal of Advanced and Applied Sciences (IJAAS)6 ( 7 )

Degenerative mitral valve disease (DMVD) is the leading cause of cardiac disease and heart failure in the dog. Advanced age, breed and male gender are well-known risk factors for DMVD. The incidence of the disease in German Shepherds seems to be noteworthy. Early diagnosis of DMVD is related to the identification of a left apical systolic murmur, characteristic of MR in a dog. Dogs with DMVD had a low frequency of arrhythmias compared to other cardiac conditions. The goal of the study was (i) to evaluate the age and gender incidences of the asymptomatic Anatolian Shepherd Dogs (ASHs) with DMVD and, (ii) to investigate the importance . . . of its clinical, radiological, electrocardiographic (ECG) findings and the correlations of those with some echo cardio logical measurements. 35 healthy ASHs (control group) and 38 ASHs with DMVD (experimental group) were used as the materials. The severity of cardiac disease was classified according to the American College of Veterinary Internal Medicine (ACVIM) consensus statement. Thirty two dogs (84.2%) were males and 6 dogs (15.8%) were females in the experimental group. The median age, the intensity of heart murmur and the severity of mitral regurgitation (MR) of the B2 dogs were bigger (p 0.05) to MVLs, vertebral heart scale (VHS), ECG findings and regurgitant jet area to LA area ratio (ARJ/LAA). The correlations between ECG findings and VHS, along with, LA/Ao and ARJ/LAA were positive (P More less

İsmail ŞEN

Article | 2022 | MANAS Journal of Agriculture, Veterinary and Life Science (MJAVL)12 ( 1 )

Detection and prevention of hypokalemia which causes economic losses and metabolic diseases in dairy cows had great importance. For this reason, the first objective of this study is to determine the level of blood potassium in dairy cows during the periparturient period and the second objective is to the determination of the relationship between metabolic diseases and blood potassium levels. A total of 60 cows were used in the study. Forty cows of them (Group I; 20 and group II;20) were pregnant and multiparous, and 20 of them with metabolic diseases (ketosis, displacement of abomasum). Blood samples of healthy cattle were taken fro . . .m v.jugularis twice, 10 ml each time. The first blood sample was taken two weeks before calving, and the second blood sample was taken within two weeks after calving. Blood samples of 20 cattle with metabolic diseases were taken from v.jugularis once, 10 ml. Serum samples were analyzed for Na, K, Cl, Creatinine, AST, LDH, Mg, P, and CPK parameters. The mean potassium level of group I and II healthy cattle after calving was 2,35 ± 0,17 mmol/l and 2,71 ± 0,12 mmol/l, respectively. However, the mean potassium level of cattle with metabolic diseases was also 2,53 ± 0,06 mmol/l. In conclusion, development of negative K balance in dairy cows after birth were detected. Additionally, cattle with displaced abomasum and ketosis were also found hypokalemic More less

İsmail ŞEN | Hasan GÜZELBEKTEŞ

Article | 2019 | Research in Veterinary Science126

Sepsis is associated with clinically relevant cardiovascular changes. The objectives of this study were to evaluate the clinical value of echocardiography for monitoring left ventricular (LV) systolic function in septic calves. A prospective longitudinal study was performed using a convenience sample. Twenty septic calves and 10 healthy calves were enrolled in the study. Arterial blood pressure (BP) was measured and M-mode echocardiography performed to characterize LV systolic function; the latter included measurement of ejection fraction, EF; stroke volume, SVI and cardiac output indexed to body weight, CI; E-point of septal separa . . .tion, EPSS; pre-ejection period, PEP; ejection time, LVET; ratio of PEP to LVET; velocity of circumferential shortening, Vcf, LV enddiastolic volume index (LVEDVI) and LV end-systolic volume index (LVESVI) on admission and 6, 24, 48 and 72 h later in septic calves and once in healthy calves. Admission data were compared using the Mann-Whitney U test and P < .05 was considered significant. Decreased preload and afterload were present in septic calves, as indicated by marked decreases in BP, LVEDVI, LVESVI, SVI, CI, EPSS when compared to healthy calves. Systolic function appeared adequate in septic calves, based on EF and FS compared to control calves. There was no difference in heart rate, LVET, PEP:LVET, or Vcf between septic and health calves. We conclude that circulatory dysfunction, rather than systolic dysfunction predominates in septic calves. Positive associations on admission between CI and LVEDVI, LVESVI, and SVI support this conclusion. Echocardiographic determination of LVEDVI and CI appears useful in directing treatment in septic calves More less

İsmail ŞEN

Article | 2022 | Journal of the Hellenic Veterinary Medical Society73 ( 2 )

This study aimed to detect changes in clinical parameters, biochemical and serum cytokine levels in calves with naturally occurring sepsis. In the study, 34 calves diagnosed with sepsis according to clinical and laboratory results and 7 calves deemed to be healthy according to clinical and laboratory results were used. The blood sampling was performed by jugular venapuncture for hematological and biochemical analysis and the determination of cytokine levels. Significant changes were observed in the clinical parameters of calves with sepsis. Serum concentrations of IL-1 beta, IL-6, IL-10, TNF-alpha, and INF-gamma were significantly i . . .ncreased ( More less

Abuzer TAŞ | İsmail ŞEN | Fatih HATİPOĞLU | Hasan Hüseyin ARI | Ruslan SALIKOV | Nur ABDIMANAP UULU | Ayperi Aytmırza Kızı

Article | 2024 | Journal of Applied Animal Research52 ( 1 )

Coenurosis caused by Coenurus cerebralis poses a significant economic threat to sheep. To date, no effective treatment has been identified for this parasitic infection once it has settled in the brain. This study aimed to investigate the surgical removal of C. cerebralis cysts from the brains of infected sheep. Twenty sheep were utilized in the experiment, and the animals underwent a 24-hour fasting period before the surgical procedure. Various biochemical parameters, including TP, ALP, BUN, AST, CK, LDH, RBC, WBC, Hb, and Hct, were measured in the animals both before and one month after the operation. Anesthesia was induced by admi . . .nistering 2.2 mg/kg IV ketamine hydrochloride, five minutes after the administration of 0.1 mg/kg IV xylazine hydrochloride. Following anesthesia, the trepanation site was determined through percussion. Subsequently, an incision was made in the skin, exposing the skull bone. The skull was opened using a scalpel through trepanation, and the cysts were carefully removed. The results demonstrated that the presented surgical technique effectively treated C. cerebralis cysts in the sheep's brains, restoring normal motor and metabolic functions. Given these outcomes, it is concluded that the proposed surgical technique holds promise for practical application in the field. Keyword: biochemical testing; haematological examination; histopathology; ovine parasite; Taenia multicep More less

İsmail ŞEN

Article | 2020 | Theriogenology158

Echocardiographic studies in human neonatology has demonstrated that prematurity can lead to cardiovascular dysfunction and especially compromises the left ventricular (LV) systolic and diastolic functions. As echocardiographic studies have not been performed on cardiovascular dysfunction in premature calves, we echocardiographically evaluated and compared the LV systolic and diastolic function in full-term and premature calves. We followed the hemodynamical changes of LV during first 3 days of life. Twenty premature calves and 10 healthy term calves were enrolled in the study. 2D, M-mode and Doppler echocardiographic examinations w . . .ere performed at days 1, 2 and 3 after birth to evaluate LV systolic and diastolic functions. Our findings demonstrated that not only was there LV diastolic dysfunction (55% premature calves, 10% term calf at day 1; 65% premature calves, 10% term calf at day 2 and, 75% premature calves, 20% term calf at day 3), but also LV systolic dysfunction (55% premature calves, 60% term calf at day 1; 55% premature calves, 50% term calf at day 2, and 45% premature calves, 40% term calf at day 3) deteriorated in both term and premature calves. In conclusion, the present study, which was the first comparative echocardiographic assessment of LV systolic and diastolic functions in term and premature newborn calves, showed that both systolic and diastolic dysfunctions might occur in term and premature calves. (C) 2020 Elsevier Inc. All rights reserved More less

İsmail ŞEN

Article | 2020 | Kafkas Üniversitesi Veteriner Fakültesi Dergisi26 ( 3 )

The aim of this study was to determine the levels of macrominerals and trace elements in the blood of newborn calves with sepsis.The study was carried out on a total of 30 calves, aged 2-35 days old, of which 25 with sepsis and 5 healthy. In clinical examination, prolonged capillary refill time and tachypnea were observed in calves with sepsis. The levels of Cu, K, P and Sin calves with sepsis were higher compared to the control group, and the levels of Na, total and ionized Ca, Fe and Zn were also lower compared to the control group. In conclusion, in this study, significant increase in K and Cu concentrations and significant decre . . .ase in Na and Ca concentrations were found in calves with sepsis. According to the results, K, Cu, Na and Ca may have important roles in the pathophysiology of sepsis More less

Hasan GÜZELBEKTEŞ | İsmail ŞEN

Article | 2018 | Journal of the Hellenic Veterinary Medical Society69 ( 4 )

In this study, it was aimed to determine of diagnostic importance of blood lipid levels in neonatal calves with sepsis. The study was carried out on a total of 70 calves, 60 with sepsis and 10 healthy calves. The calves with sepsis were included in the study, according to clinical and hematological findings. The blood samples were taken from the V. jugularis for hematological, lipid profile and biochemical analyzes after the routine clinical examinations of the calves. There were significantly (P < 0.05) decrease in body temperature, increase in respiration rate and capillary refill time in the calves with sepsis compared to control . . . group. The levels of blood urea nitrogen, creatinine concentrations of calves with sepsis were significantly higher (P < 0.05), however, levels of total cholesterol, HDL and LDL concentrations were significantly lower (P < 0.05) than control group. In addition, blood triglyceride and VLDL concentrations of calves with sepsis were higher than control group, however there was no statistical difference. In conclusion, serum total cholesterol, HDL and LDL in neonatal calves with sepsis could be used in evaluation of the sepsis in calves More less

İsmail ŞEN

Review | 2021 | Frontiers in Veterinary Science7

Optimal fluid therapy protocols in neonatal calves and adult cattle are based on consideration of signalment, history, and physical examination findings, and individually tailored whenever laboratory analysis is available. Measurement of the magnitude of eye recession, duration of skin tenting in the lateral neck region, and urine specific gravity by refractometry provide the best estimates of hydration status in calves and cattle. Intravenous and oral electrolyte solutions (OES) are frequently administered to critically ill calves and adult cattle. Application of physicochemical principles indicates that 0.9% NaCl, Ringer

İsmail ŞEN

Review | 2023 | Canadian Veterinary Journal64 ( 9 )

The term sepsis-induced cardiomyopathy (SIC) is used to describe transient cardiac dysfunction in septic patients. However, there is no universally accepted definition of SIC; a reduction in left ventricular ejection fraction (LVEF) is often used. In addition to systolic dysfunction, diastolic dysfunction is now recognized as an essential component of SIC. It can be emphasized that previous animal experiments played an essential role in revealing SIC and hemodynamic instability in sepsis and septic shock. The diagnostic and prognostic capabilities of echocardiography for the assessment of SIC have been extensively studied since its . . .introduction into intensive care clinical practice. Recent studies in dogs, calves, and horses have shown that left and right ventricular systolic dysfunction, left ventricular diastolic dysfunction, and circulatory dysfunction can occur in sepsis, severe sepsis, and septic shock in animals. Echocardiographic variables have also shown that indices of left and right ventricular dysfunction and circulatory failure are valuable indicators of mortality in septic animals More less

İsmail ŞEN

Article | 2019 | Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi33 ( 3 )

Bu çalışmanın amacı, yenidoğan ishalli buzağılarda prognoz ve mortalite indikatörü olarak hangi parametrelerin kullanılabileceğini araştırmaktı. Araştırmada 51 yenidoğan ishalli buzağı kullanıldı. İshalli buzağılar ölen (n=16) ve hayatta kalan (n=35) olarak iki gruba ayrıldı. Tüm buzağıların rutin klinik muayeneleri yapıldıktan sonra hematolojik, kan gazları ve biyokimyasal analizler için kan alındı. Tüm buzağılarda ishal, dehidrasyon, emme refleksinde azalma, kapiler tekrar dolum zamanında uzama, hipotermi ve solunum sayısında artış belirlendi. Ölen ve hayatta kalan buzağılarda Şiddetli metabolik asidoz ve hiperkalemi mevcuttu. Hay . . .atta kalan buzağılar ile karşılaştırıldığında ölen ishalli buzağıların kan laktat seviyesi önemli oranda ( More less